PHOSPHATIDYLSERINE AS A TUMOR TARGET FOR CAR-T CELL THERAPY

Phosphatidylserine as a tumor target for CAR-T cell therapy

Background Phosphatidylserine (PS) exposed on apoptotic cells promotes immune clearance of dead cells without inducing inflammation.Conversely, PS exposure on live tumor cells promotes an immunosuppressive tumor microenvironment that hinders antitumor immune responses.After confirming elevated PS levels in various tumor cell lines and cancer tissue

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Individuality in harpsichord performance: Disentangling performer- and piece-specific influences on interpretive choices

Although a growing body of research has examined issues related to individuality in music performance, few studies have attempted to quantify markers of individuality that transcend pieces and musical styles.This study aims to identify such meta-markers by discriminating between influences linked to specific pieces or interpretive goals and perform

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Nuclear Fission Dynamics: Past, Present, Needs, and Future

Significant progress in the understanding of the fission process within a microscopic framework has been recently reported.Even though the complete description of this important nuclear reaction remains a computationally demanding task, recent developments in theoretical modeling and computational power have brought current microscopic simulations

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